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 Oxytocin

Buy Oxytocin is a naturally occurring nonapeptide hormone composed of nine amino acids. It is synthesized in the hypothalamus and released by the posterior pituitary gland. Often dubbed the “love hormone” or “bonding hormone,” oxytocin plays a central role in social bonding, maternal behavior, sexual reproduction, and childbirth.

In synthetic form, oxytocin is produced via recombinant DNA technology or solid-phase peptide synthesis. It is available as a lyophilized powder or injectable solution, and is widely used in both clinical and research settings.

Origin and Historical Development

Oxytocin was first discovered in the early 20th century:

• 1906: British physiologist Sir Henry Dale identified a substance that caused uterine contractions, later named oxytocin.
• 1953: Vincent du Vigneaud synthesized oxytocin in the lab, earning the Nobel Prize in Chemistry. This marked the first successful synthesis of a peptide hormone.
• Since then, oxytocin has been studied extensively for its endocrine, neurological, and behavioral effects.

Today, oxytocin is manufactured by pharmaceutical companies and peptide suppliers for medical use, laboratory research, and experimental therapies.

Research Applications

Oxytocin is a powerful tool in modern science, especially in the fields of neuroscience, psychology, and reproductive biology:

1. Social and Behavioral Research

• Oxytocin is studied for its role in empathy, trust, attachment, and social cognition.
• It’s used in experiments exploring autism spectrum disorders, schizophrenia, and social anxiety.

2. Neuroendocrine Studies

• Researchers investigate how oxytocin modulates stress responses, cortisol levels, and emotional regulation.
• It’s often administered intranasally in controlled trials to study its effects on brain activity and mood.

3. Reproductive Physiology

• Oxytocin is essential for uterine contractions during labor and milk ejection during breastfeeding.
• In vitro studies use oxytocin to examine smooth muscle function, hormonal feedback loops, and fertility mechanisms.

4. Cellular and Molecular Research

• Oxytocin is used in receptor binding assays, signal transduction studies, and gene expression analysis.
• It helps map G-protein-coupled receptor (GPCR) pathways and intracellular signaling cascades.

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Storage and Handling Guidelines

Proper storage is critical to maintain oxytocin’s stability and potency:

• Form: Supplied as a lyophilized (freeze-dried) powder or liquid ampoule.
• Temperature:
  • Lyophilized powder: Store below 25°C; refrigerate at 2–8°C after reconstitution.
  • Injectable solutions: Require cold chain storage at 2–8°C to prevent degradation3.
• Light Sensitivity: Protect from direct sunlight and UV exposure.
• Reconstitution:
  • Use sterile or bacteriostatic water.
  • Avoid shaking; gently swirl to dissolve.
  • Use within 24–72 hours after mixing, depending on formulation and storage conditions.
• Shelf Life: Typically 2–3 years if stored properly. Stability decreases significantly at temperatures above 25°C.

Legal and Regulatory Compliance

Oxytocin is regulated as a prescription drug and research chemical, depending on its intended use:

1. Medical Use

• Approved for clinical use in labor induction, postpartum hemorrhage prevention, and lactation support.
• Requires a prescription and must be administered by qualified healthcare professionals.

2. Research Use Only (RUO)

• Many suppliers label oxytocin as “For Research Use Only”, meaning it cannot be used in humans or animals outside of approved studies1.
• Researchers must follow institutional protocols, ethical guidelines, and biosafety standards.

3. Import and Distribution

• Importing oxytocin for research requires:
  • Documentation of research intent
  • Institutional affiliation
  • Compliance with national drug control laws
• In countries with strict pharmaceutical regulations, oxytocin may be classified as a controlled substance, requiring special licenses.

4. WHO Guidelines

• The World Health Organization (WHO) recommends oxytocin be stored in cold chain conditions, especially in hot climates (Zones III & IV).
• Products not meeting these standards may be rejected during procurement or regulatory review.

5. Safety and Ethics

• Oxytocin must not be used as a cosmetic, dietary supplement, or recreational substance.
• Misuse can result in legal penalties, loss of research privileges, and institutional sanctions.

Oxytocin is a fascinating molecule that bridges the gap between biology and behavior, offering insights into everything from childbirth to emotional bonding. Its synthetic form, widely available for research, allows scientists to explore its effects in controlled environments—but only with proper handling and legal oversight.

Whether you’re studying its role in neuroendocrine signaling, social cognition, or reproductive health, oxytocin demands precision, ethical responsibility, and scientific rigor.

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